刘克玄,男,教授、主任医师,博士生导师,博士。
医疗特长:
擅长心胸外科手术及肝胆胃肠手术的麻醉、肝肾移植手术的麻醉、术后急性疼痛治疗
研究方向:围术期肠损伤的机制及防治
主要教育和工作经历:
1998.9~2001.7 中山大学附一院麻醉学 硕士学位
2002.9~2004.7 中山大学附一院 博士学位
2005.2~2007.2 芬兰坦佩雷大学医院心脏中心 博士后研究及心脏麻醉临床培训
2008.4~2008.5 瑞士苏黎世大学 短期访问学者
2009.2.9~2009.2.13 新西兰奥克兰大学医院 麻醉与复苏高级临床技能培训
2010.5.12~ 2010.5.22 英国格拉斯哥大学医院 高级临床技能培训
2000.7 ~ 至今 中山大学附一院麻醉科 分别任主治医师、副教授、教授、主任医师、研究员、博士生导师、科副主任
社会兼职:
1. 中华医学会麻醉学分会 青年委员
2. 中华医学会麻醉学分会 器官移植学组 委员
3. 中华医学会麻醉学分会 心胸麻醉学组 委员
4. 广东省医学会麻醉学分会 委员
5. 广东省医师协会麻醉医师分会 委员
6. 广东省医学会麻醉学分会 心胸麻醉学组 委员
论著:
1. Zhou J, Huang WQ, Li C, Wu GY, Li YS, Wen SH, Lei WL, Liu KX*(刘克玄).Intestinal ischemia/reperfusion enhances microglial activation and induces cerebral injury and memory dysfunction in rats. Crit Care Med 2012; 40(8):2438-48. *Corresponding author (2011 IF: 6.33)
2. Zhang XY, Liu ZM, Wen SH, Li YS, Li Y, Yao X, Huang WQ, Liu KX*(刘克玄). Dexmedetomidine Administration before, but Not after, Ischemia Attenuates Intestinal Injury Induced by Intestinal Ischemia-Reperfusion in Rats. Anesthesiology. 2012;116(5):1035-46. *Corresponding author (2011 IF: 5.359)
3. Li C, Li YS, Xu M, Yao X, Wu Y, Huang CY, Huang WQ, Liu KX*(刘克玄). Limb remote ischemic preconditioning for intestinal and pulmonary protection during elective open infrarenal abdominal aortic aneurysm repair: a randomized controlled trial. Anesthesiology 2012; *Corresponding author (2011 IF: 5.359)
4. Liu KX*(刘克玄), Xia Z. Potential synergy of antioxidant N-acetylcysteine and insulin in restoring sevoflurane postconditioning cardioprotection in diabetes. Anesthesiology. 2012;116(2):488-9. *Corresponding author (2011 IF: 5.359)
5. Liu KX*(刘克玄), Li YS, Huang WQ, et al. Immediate postconditioning during reperfusion attenuates intestinal injury. Intensive Care Med 2009; 35(5): 933–942 (2011 IF: 5.399) *Corresponding author
6. Liu KX*(刘克玄), Li YS, Huang WQ. Reply to Oltean and Olausson. Intensive Care Med 2010;36(6):1096 *Corresponding author (2011 IF: 5.399)
7. Liu KX*(刘克玄), Li C,Li YS, Yuan BL, Xu M, Xia Z, Huang WQ. Proteomic analysis of intestinal ischemia/reperfusion injury and ischemic preconditioning in rats reveals the protective role of aldose reductase. Proteomics 2010 ;10(24):4463-75. (2011 IF: 4.515) *Corresponding author
8. Wen SH, Ling YH, Li Y, Li C, Liu JX, Li YS, Yao X, Liu KX*(刘克玄). Ischemic Postconditioning during Reperfusion Attenuates Oxidative Stress and Intestinal Mucosal Apoptosis Induced By Intestinal Ischemia/Reperfusion via Aldose Reductase. Surgery 2012 (2011 IF: 3.406) *Corresponding author
9. Liu KX*(刘克玄), Chen SQ, Huang WQ, Li YS, Irwin MG, Xia Z. Propofol pretreatment reduces ceramide production and attenuates intestinal mucosal apoptosis induced by intestinal ischemia/reperfusion in rats. Anesth & Analg 2008; 107(12):1884 –91. *Corresponding author (2011 IF: 3.286)
10. Wen SH, Li Y, Li C, Xia ZQ, Liu WF, Zhang XY, Lei WL, Huang WQ, Liu KX*(刘克玄). Ischemic Postconditioning During Reperfusion Attenuates Intestinal Injury and Mucosal Cell Apoptosis by Inhibiting JAK/STAT Signaling Activation. Shock 2012 Jul 6 *Corresponding author (2011 IF: 3.32)
11. Liu KX*(刘克玄), Li YS, Huang WQ, et al. Immediate but not delayed postconditioning during reperfusion attenuates acute lung injury induced by intestinal ischemia/reperfusion in rats: comparison with ischemic preconditioning. J Surg Res 2009; 157(1)e:55-62 (2011 IF: 2.247) *Corresponding author
12. Liu KX(刘克玄)*,Chen SQ, Zhang H, Guo JY, Li YS, Huang WQ. Intestinal ischemia/reperfusion upregulates β-defensin-2 expression and causes acute lung injury in the rat. Injury 2009,40(5): 950-955 (2011 IF:1.975) *Corresponding author
13. Liu KX*(刘克玄),Rinne T, He W, Wang F, Xia Z. Propofol pretreatment attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rats. Can J Anaesth 2007, 54(5):366-74 *Corresponding author (2011 IF: 2.346)
14. Liu KX*(刘克玄), He W, Rinne T, Liu Y, Zhao MQ, Wu WK. The effect of Gingo biloba (EGb 761) pretreatment on intestinal epithelial apoptosis induced by intestinal ischemia/reperfusion in rats: role of ceramide. Am J Chin Med 2007,35(5):233 *Co-corresponding author (2011 IF: 1.979)
15. Liu KX*(刘克玄), Wu WK, He W, Liu CL. Ginkgo biloba extract (EGb 761) attenuates lung injury induced by intestinal ischemia/reperfusion in rats: Roles of oxidative stress and nitric oxide. World J Gastroenterol 2007;13(2): 299-305. *Corresponding author (2011 IF: 2.44)
16. Li YS, Wang ZX, Li C, Xu M, Li Y, Huang WQ, Xia Z, Liu KX(刘克玄)*.Proteomics of ischemia/reperfusion injury in rat intestine with and without ischemic postconditioning. J Surg Res 2010;164(1):e173-80 (2011 IF: 2.247) *Corresponding author
17. Li C, Chen SQ, Chen BX, Huang WQ, Liu KX(刘克玄)*. The antinociceptive effect of intrathecal tramadol in rats: the role of alpha 2-adrenoceptors in the spinal cord. J Anesth. 2011;26(2):230-5. (2011 IF: 0.85). *Corresponding author
专著:
其他主要工作成绩(比如获奖情况):
1. 入选“教育部新世纪优秀人才支持计划”
2. 入选中山大学附属第一医院“优秀青年科技人才支持计划”
3. 2010 中层干部年度考核“优秀”
4. 广州市抗击非典“三等功”; 广东省抗击非典“先进个人”
5. 连续三年医院年度考核“优秀”
6. 2010年度院级优秀共产党员; 2011年及2012年度校级优秀共产党员