王欣的个人首页

　　王欣，女，1991年毕业于天津医科大学，获得学士学位;

　　2001年毕业于瑞典隆德大学医学，获得医学博士学位。

　　抗癌协会乳腺癌专业委员会青年委员

　　《中华肿瘤防治杂志》编委

　　《中国肿瘤临床》杂志英文版编委

　　2007年获得天津市科学技术进步三等奖。(项目：肋间臂神经解剖生理学及在乳腺功能外科的应用, 2007JB-3-164-R3)。具有GCP资格，能主持临床试验。已完成天津市高等学校科技发展基金计划项目，CysLT1和CysLT2受体与乳腺癌相关性的研究，并已成果鉴定。承担国家自然科学基金，肿瘤生长抑制因子Rb通过控制能量代谢平衡调节细胞转化作用的机制研究(第二承担人)。座客北方网健康大讲堂《乳腺癌的解读和防治》

　　共发表论文40余篇，其中SCI收录文章29篇。担当《现代乳腺疾病治疗学》(2007年人民卫生出版社)副主译。培养硕士研究生，带教进修生和实习医生。参与天津医科大学的留学生教学工作。

　　(1) Yunwei Han, Zhihao Yu, Shaoyan Wen, Bin Zhang, Xuchen Cao, Xin Wang. Prognostic value of chemotherapy-induced neutropenia in early-stage breast cancer. Breast Cancer Res Treat 2012; 131:483–490. (通讯作者)

　　(2) 马祥敏，崔文静，张矫，王欣.老年人乳腺癌综合治疗研究进展.中华老年医学杂志2012;31(5):442-444. (通讯作者)

　　(3) 韩芸蔚，常新忠，温绍艳，王欣。男性和女性乳腺癌临床病理特征的配对比较及生存分析.中华内分泌外科杂志2012;6(2):102-105。(通讯作者)

　　(4) 韩芸蔚，王欣，张斌，温绍艳，刘伟，曹旭晨。新辅助化疗诱导的粒细胞减少症对乳腺癌预后的影响.中华普通外科杂志2011;8(26):651-654. (通讯作者)

　　(5) 温绍艳，韩芸蔚，马祥敏，等.三阴性乳腺癌的钼靶影像学表现和临床病理特征[J].中华肿瘤杂志，2012，34(4):291-295。(通讯作者)

　　(6) 温绍艳，王欣，曹旭晨.新辅助化疗乳腺癌前哨淋巴结活检时机的选择问题[J].中国肿瘤外科杂志，2012，4(2):108-111(通讯作者)

　　(7) 韩芸蔚，温绍艳，刘伟，王欣。乳腺癌新辅助化疗的临床评价进展.中国肿瘤临床2011;38(7):408-411. (通讯作者)

　　(8) 刘伟，李越，赵颖，等.乳腺癌腋窝淋巴结B超检查特异性回顾性分析.中国实用外科杂志2011;31(1):96-99. (通讯作者)

　　(9) 刘伟，韩芸蔚，温绍艳，等.乳腺中央型及外周型乳头状瘤癌变的外科治疗中国肿瘤临床，2011;38(10):574-577. (通讯作者)

　　(10) Wang X，Zhao Y and Cao X. Clincal benefits of mastectomy on treatment of occult breast csrcinoms presenting axillary metastases. The Breast Journal 2010;16:32-37.(通讯作者)

　　(11) 于治灏，李越，王欣.Angiomotin在乳腺癌中的研究进展.中华乳腺病杂志2010;4:53-56.(通讯作者)

　　(12) 李越,王欣,赵颖,葛洁,张斌,于治灏,宁连胜,曹旭晨.超声光散射乳腺成像诊断乳腺癌假阳性率分析.中国肿瘤临床.2010;37:704-6. (通讯作者)

　　(13) 王欣，李越，赵颖，葛洁，张斌，宁连胜，曹旭晨.光学功能成像技术在乳腺癌早期诊断中的应用.中华乳腺病杂志2009,3(4):42-45.

　　(14) 李越，赵颖，张斌，葛洁，宁连胜，曹旭晨，于治灏，王欣.超声光散射乳腺成像诊断乳腺癌的临床价值.中华乳腺病杂志2009,3(4):20-24.(通讯作者)

　　(15) 李越，王欣，于治灏，赵颖，宁连胜，曹旭晨.乳腺Paget’s病的临床病理分析.中国肿瘤临床2009,36(17):980-982. (通讯作者)

　　(16) 李越，王欣5-FU代谢酶基因型多态性与乳腺癌化疗敏感相关性研究的进展.中华肿瘤防治杂志2009,16(15):1192-1195. (通讯作者)

　　(17) 闫哲，王欣. Cystatins与肿瘤发生发展关系的研究现状。中华乳腺病杂志2008;2(5):47-51.(通讯作者)

　　(18) 王欣，闫哲，李晓青，冯玉梅和曹旭晨。Cystatin M在乳腺癌及转移癌中的表达和临床意义。中华乳腺病杂志2008;2(3):21-25.

　　(19) Wang X and Ning L. Breast carcinoma associated with Poland’s syndrome: One case report and literatures. Chinese Journal of Clinical Oncology 2008;5(3): 223-225.

　　(20) Wang X, Cao X and Ning L. Traumatic neuromas after mastectomy. ANS J Surg. 2007; 77:1.

　　(21) 王欣，宁连胜. Poland综合征合并乳腺癌1例报道及文献回顾.中国肿瘤临床2008;35(2):78-79.

　　(22) Wahlbom M, Wang X, Lindström V, Carlemalm E, Jaskolski M and Grubb A. Fibrillogenic oligomers of human cystatin C are formed by propagated domain swapping. J Biol Chem. 2007;282(25):18318-26.

　　(23) Wang X, Cao X and Ning L. Traumatic Neuromas in breast cancer patients after mastectomy. Chinese J of Clinical Oncology 2007;4(3):185-188.

　　(24) Wang X. Presentation of Axillary Metastases from Occult Breast Carcinoma. Chinese J of Clinical Oncology 2007;4:1-5.

　　(25) Selenica M, Wang X, Pedersen LO, Grubb A and Westlind-Danielsson A. Cystatin C Reduces the Formation of Soluble A1-42 Oligomers and Protofibrils. Scand J Clin Lab Invest 2007;67(2):179-90.

　　(26) Ning L, Wang X, Zhao K, et al. Anatomical study of intercostobrachial never in SD rat. Chinese J of Clinical Oncology 2006;3:118-121.

　　(27) Rodziewicz-Motowidio, S, Wahlbom M, Wang X, et al. Checking the conformational stability of cystatin C and its L68Q variant by molecular dynamics studies: Why is the L68Q variant amyloidogenic? Journal of Structural Biology 2006;154(1):68-78.

　　(28) Nilsson M, Wang X, Rodziewicz-Motowidlo S, et al. Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C - Use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C. JOURNAL OF BIOLOGICAL CHEMISTRY 279 (23): 24236-24245 JUN 4 2004 [共享第一作者](SCI收录)

　　(29) Chen D, Zhao CM, Wang X, et al. Target for gene therapy of gastric cancer: Gastrin? Helicobacter pylori infection may result in gastric cancer in hypergastrinemic mice but not in gastrin-deficient mice. CANCER GENE THERAPY 11 (12): 851-851 P6 DEC 2004 (SCI收录)

　　(30) Zhao CM, Wang X, Friis-Hansen L, et al. Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. REGULATORY PEPTIDES 115 (3): 161-170 OCT 15 2003. (SCI收录)

　　(31) Liuba P, Pesonen E, Paakkari I, et al. Co-infection with Chlamydia pneumoniae and Helicobacter pylori results in vascular endothelial dysfunction and enhanced VCAM-1 expression in ApoE-knockout mice. JOURNAL OF VASCULAR RESEARCH 40 (2): 115-122 MAR-APR 2003. (SCI收录)

　　(32) Wang X, Willen R, Svensson M, et al. Two-year follow-up of Helicobacter pylori infection in C57BL/6 and Balb/cA mice. APMIS 111 (4): 514-522 APR 2003 (SCI收录)

　　(33) Chen D, Zhao CM, Wang X, et al. Disparate effects of chronic Helicobacter pylori infection on parietal cells and ECL cells in wild-type vs gastrin-deficient mice. INTERNATIONAL JOURNAL OF CANCER : 220-220 Suppl. 13 2002 (SCI收录)

　　(34) Wang X: Helicobacter pylori infection in a mouse model: Development, optimization and inhibitory effects of antioxidants. Doctoral thesis, 2001, Department of Medical Microbiology, Dermatology and Infection, University of Lund, Lund, Sweden. (http://www.lub.lu.se/luft/diss/med558_transit.html)

　　(35) Wang X, Hirmo S, Willén R, Wadström T. Inhibition of Helicobacter pylori infection by bovine milk glycoconjugates in a BALB/cA mouse model. J Med Microbiol 2001; 50: 430-435. (SCI收录)

　　(36) Wang X, Willen R, Wadstrom T: Astaxanthin-rich algal meal and vitamin C inhibit Helicobacter pylori infection in BALB/cA mice. Antimicrob Agents Chemother 2000;44(9):2452-7. (SCI收录)

　　(37) Wang X, Willen R, Andersson C, Wadstrom T: Development of high-grade lymphoma in Helicobacter pylori-infected C57BL/6 miceNote. Apmis 2000;108(7-8):503-508. (SCI收录)

　　(38) Wang X, Sjunnesson H, Sturegård E, Wadström T, Willén R and Aleljung P. Dietary factors influence the recovery rates of Helicobacter pylori in a BALB/cA mouse model. B&K Science Now 2000;9:1-6. (SCI收录)

　　(39) Willen R, Carlen B, Wang X, Papadogiannakis N, Odselius R, Wadstrom T: Morphologic conversion of Helicobacter pylori from spiral to coccoid form. Scanning (SEM) and transmission electron microscopy (TEM) suggest viability. Ups J Med Sci 2000;105(1):31-40. (SCI收录)

　　(40) Bennedsen M, Wang X, Willen R, Wadstrom T, Andersen LP: Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol Lett 1999;70(3):185-9. (SCI收录)

　　(41) Wang X, Sjunnesson H, Sturegard E, Wadström T, Willén R, Aleljung P: Dietary factors influence the recovery rates of Helicobacter pylori in a BALB/cA mouse model. Zentralbl Bakteriol 1998;288(2):195-205. (SCI收录)

　　(42) Wang X, Willén R, Wadström T, Aleljung P: RAPD-PCR, histopathological and serological analysis of four mouse strains infected with multiple strains of Helicobacter pylori. Microbial Ecology in Health and Disease 1998;10:148-154. (SCI收录)

　　(43) Wang X, Sturegard E, Rupar R, Nilsson HO, Aleljung PA, Carlén B, Willén R, Wadström T: Infection of BALB/c A mice by spiral and coccoid forms of Helicobacter pylori. J Med Microbiol 1997;46(8):657-63. (SCI收录)

　　(44) Aleljung P, Nilsson HO, Wang X, Nyberg P, Morner T, Warsame I, Wadström T: Gastrointestinal colonisation of BALB/cA mice by Helicobacter pylori monitored by heparin magnetic separation. FEMS Immunol Med Microbiol 1996;13(4):303-9. (SCI收录)

　　门诊时间：周一下午，周三、周五上午乳腺肿瘤门诊