蔡坚的个人首页

　　蔡坚，女，副主任医师。

　　医疗专长：

　　1. 胃癌、结直肠癌、胰腺癌、食管癌、腹膜后肿瘤、间质瘤、腹部神经内分泌肿瘤等的诊断、手术治疗和个体化综合治疗。胃肠道肿瘤、间质瘤等微创治疗和个体化靶向治疗。 2. 结直肠肛门炎症性疾病、良性肿瘤、痔、脱垂等疾病的诊断与治疗。 3. 消化道疾病的胃镜或肠镜下诊断与治疗。 4. 腹部手术相关并发症的诊断与治疗。 5. 围手术期营养评估和肠内外营养治疗。 6. 家族性遗传性胃肠道肿瘤的筛查、诊断和治疗。

　　主要研究方向：

　　1.胃肠胰腺肿瘤早期诊断、外科治疗和个体化靶向治疗 2.家族性遗传性胃肠胰腺肿瘤的诊治

　　社会兼职

　　1.广东省胃肠外科学分会委员兼秘书 2.美国抗癌协会会员

　　论　　著

　　1. Zhang CH, Zhan WH, He YL, et al. Spleen preservation in radical surgery for Gastric cardiac cancer. Ann Surg Oncolog, 2007v14(4) 1312-1319 (IF 4.166) 2. Xu JB, Zhang CH(共同第一作者), He YL, et al. Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer. Int J Cancer. 2012 Feb 15;130(4):787-97(IF 5.44) 3. Zhang C, Awasthi N, Schwarz MA, Hinz S, Schwarz RE. Superior antitumor activity of nanoparticle albumin-bound Paclitaxel in experimental gastric cancer. PLoS One. 2013;8(2):e58037. doi: 10.1371/journal.pone.0058037. (IF 4.1) 4. Zhang CH, Song XM, He YL, et al. Use of absorbable hemostatic gauze with medical adhesive is effective for achieving hemostasis in presacral hemorrhage. Am J Surg. 2012 Apr;203(4):e5-8 (IF 2.776) 5. Zhang CH, He YL, Wang FJ, et al. Detection of hMSH2 and hMLH1 mutations in Chinese Hereditary Non-polyposis Colorectal Cancer kindreds. World J Gastroenterol 2008; 14 (2)：298-302 (IF 2.47) 6. Zhang C, Awasthi N, Schwarz MA, Schwarz RE. Establishing a peritoneal dissemination xenograft mouse model for survival outcome assessment of experimental gastric cancer. J Surg Res. 2012 Nov 15. pii: S0022-4804(12)00971-7. doi: 10.1016/j.jss.2012.10.052 (IF 2.2) 7. Awasthi N, Zhang C, Ruan W, Schwarz MA, Schwarz RE. BMS-754807, a Small-Molecule Inhibitor of Insulin-like Growth Factor-1 Receptor/Insulin Receptor, Enhances Gemcitabine Response in Pancreatic Cancer. Molecular cancer therapeutics 2012;11: 2644-53 (IF 5.2) 8. Awasthi N, Zhang C, Ruan W, et al. Evaluation of poly-mechanistic antiangiogenic combinations to enhance cytotoxic therapy response in pancreatic cancer. PLoS One 2012; 7(6):e38477. eISSN-1932-6203 (IF 4.1) 9. Xiyu Yuan, Changhua Zhang, Yulong He, et al. Is Albumin administration beneficial in early stage of postoperative hypoalbuminemia following gastrointestinal surgery?:A prospective randomized controlled trial. Am J Surg. 2008 Nov;196(5):751-5. (IF 2.776) 10. He YL, Zhang CH, Huang MJ, et al. Clinical analysis of eight kindreds of familial adenomatous polyposis. World J Gastroenterol 2004; 10(24): 3659-366 (IF 2.47)

　　专　　著

　　《胃癌淋巴转移》副主编，人民卫生出版社，2011。